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This pilot study investigates the therapeutic potential of modulators of the glucagon-like peptide 1 (GLP-1) and neuropeptide Y (NPY) system using GLP-1 receptor agonists (semaglutide) and antagonists (exendin 9-39), as well as non-selective and NPY-Y2-receptor selective peptide tyrosine tyrosine (PYY) analogs (PYY3-36/NNC0165-0020 and NNC0165-1273) and an NPY-Y2 receptor antagonist (JNJ31020028)

Eli Lilly's GLP-1 Drugs Mounjaro & Zepbound Saw Massive 2025 Sales Growth Sales of two GLP-1 medications from Eli Lilly (NYSE: LLY) experienced significant growth in 2025, according to a report from Yahoo Finance

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GLP-1s functions inside our heads include regulating insulin signalling in the brain